Cat: IPD-X28589

Recombinant Human CEP55 Protein,His

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Analytical Data

  • 基因名

    CEP55

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CT111; URCC6; C10orf3; Cancer/Testis Antigen 111; Up-regulated in colon cancer 6

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 95% as determined by SDS-PAGE.

  • 蛋白编号

    Q53EZ4

  • 表达区间

    Gln189~Lys464

  • 分子量

    38kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CEP55, or Centrosomal Protein 55, is an essential component in the process of cytokinesis, the final stage of cell division, where the cytoplasm of a parental cell is divided into two daughter cells. Researchers have increasingly focused on CEP55 due to its critical role in ensuring proper cell division and its implications in various diseases, particularly cancer. Abnormal expression levels of CEP55 have been correlated with tumorigenesis and cancer progression, making it a potential biomarker and therapeutic target. The protein functions through interactions with several key regulators of cytokinesis, such as the septins and other cytoskeletal proteins, which helps maintain the structural integrity of the dividing cell. Additionally, CEP55 is also involved in the regulation of the mitotic spindle assembly and cell cycle progression, indicating its multifaceted role in cell biology. As understanding the molecular mechanisms underlying CEP55 function continues to evolve, researchers are investigating its potential applications in targeted cancer therapies and diagnostic tools, thus highlighting its significance in both fundamental research and clinical settings. The development of recombinant CEP55 protein has facilitated studies on its structure-function relationship and its interactions with other cellular components, paving the way for advancements in cancer research and therapeutic interventions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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