Analytical Data
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基因名
PANX1
- Application
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别名
MRS1; PX1; Innexin
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P60570
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表达区间
Ala77~Asp260
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分子量
22kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PANX1 (Pannexin 1) is a large-pore channel protein expressed in various tissues, playing a critical role in intercellular communication, cell signaling, and various physiological processes. Research on PANX1 has gained momentum due to its involvement in diverse biological functions, including the regulation of apoptosis, neurotransmission, and inflammation. Dysregulation of PANX1 has been implicated in several pathological conditions, including neurological disorders, cancer, and cardiovascular diseases. The recombinant expression of PANX1 is crucial for understanding its structure-function relationship and examining its roles in cellular processes. By generating recombinant PANX1 proteins, researchers can study the channel's biophysical properties and its interactions with various ligands and cellular components. Furthermore, these studies aid in the development of potential therapeutic interventions targeting PANX1-related pathways. Overall, the investigation of recombinant PANX1 offers valuable insights into its contribution to cellular homeostasis and disease mechanisms, highlighting its relevance as a potential therapeutic target.
