Analytical Data
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基因名
GABRR1
- Application
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别名
GABA(A) receptor subunit rho-1; GABA(C) receptor
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P24046
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表达区间
Thr22~Ile281
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分子量
61kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GABRR1 (Gamma-Aminobutyric Acid Type A Receptor Subunit R1) is a crucial member of the GABAA receptor family, which plays an essential role in mediating inhibitory neurotransmission in the central nervous system. This receptor is particularly important in regulating neuronal excitability and maintaining the balance of excitation and inhibition in the brain. Research into GABRR1 is significant due to its potential involvement in various neurological and psychiatric disorders, including anxiety, epilepsy, and depression. The study of GABRR1 recombinant proteins allows scientists to explore the structure-function relationships of this receptor, assess its pharmacological properties, and investigate its interactions with different ligands. By developing and characterizing GABRR1 recombinant proteins, researchers can better understand the receptor's role in cellular signaling and its impact on synaptic transmission. Furthermore, recombinant GABRR1 proteins can serve as valuable tools for drug discovery, enabling the identification of novel therapeutic agents that target specific subtypes of GABAA receptors. Overall, advancing our understanding of GABRR1 through recombinant protein research holds great promise for developing new treatments for a range of neurological conditions, highlighting the importance of continued investigation in this field.
