Analytical Data
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基因名
PE-Labeled ACE2
- Application
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别名
ACEH; ACEII; ACE-II; Peptidyl-Dipeptidase A; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15
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种属
Cynomolgus
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表达系统
HEK293
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标签
C- hFc
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纯度
Greater than 93% as determined by SDS-PAGE.
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蛋白编号
A0A2K5X283
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表达区间
18-741aa
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蛋白长度
Partial
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分子量
112.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of PE-labeled ACE2 recombinant proteins has emerged from the increasing interest in understanding the interactions between the angiotensin-converting enzyme 2 (ACE2) and the SARS-CoV-2 virus, responsible for the COVID-19 pandemic. ACE2 serves as a critical receptor for the spike protein of the virus, facilitating its entry into human cells. By utilizing PE (phosphatidylethanolamine) labeling, researchers aim to enhance the stability and functionality of ACE2, thereby improving its application in therapeutic and diagnostic settings. The PE-labeled ACE2 recombinant proteins can aid in elucidating the molecular mechanisms of viral entry and pathogenesis, and they hold potential as tools for developing antiviral strategies, such as inhibitors or vaccines. Moreover, these proteins can be instrumental in studying the role of ACE2 in cardiovascular diseases and other conditions where its activity is altered. Overall, the research on PE-labeled ACE2 recombinant proteins not only contributes to the fundamental understanding of viral-host interactions but also opens up avenues for innovative therapeutic interventions.
