Analytical Data
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基因名
UPK2
- Application
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别名
UPII; Uroplakin II
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
O00526
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表达区间
Asp26~Thr153
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分子量
17kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UPK2 (Uroplakin 2) is a member of the uroplakin family of proteins, predominantly expressed in the urothelial cells of the bladder. This protein plays a crucial role in maintaining the integrity of the urothelium, which serves as a barrier against pathogens and toxins in the urinary system. Research on UPK2 and its recombinant protein has gained importance due to its potential involvement in bladder-related disorders, including urinary tract infections, bladder cancer, and interstitial cystitis. Understanding UPK2's structure and function is essential for elucidating its role in cellular signaling pathways and urinary bladder pathophysiology. The production of recombinant UPK2 protein allows scientists to study its biochemical properties, interactions with other cellular components, and its behavior in disease models. Additionally, recombinant UPK2 could be used to develop diagnostic tools or therapeutic strategies for bladder diseases. This research area holds promise for improving clinical outcomes and advancing our understanding of bladder health and diseases, highlighting the significance of UPK2 as both a biomarker and a potential target for novel therapies.
