Analytical Data
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基因名
LAMP5
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简介
LAMP5 Protein significantly contributes to short-term synaptic plasticity in a specific subset of GABAergic neurons in the brain. LAMP5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived LAMP5 protein, expressed by HEK293 , with C-hFc labeled tag.
- Application
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别名
BAD-LAMP; LAMP-5; BADLAMP; C20orf103; dJ1119D9.3; UNC-43
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种属
Mouse
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9D387
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表达区间
E30-E235
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蛋白长度
Extracellular Domain
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分子量
60-70 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LAMP5 (Lysosomal-associated membrane protein 5) is a member of the LAMP protein family, which plays a crucial role in lysosomal function and cellular homeostasis. This protein is primarily expressed in the nervous system, where it has been implicated in various physiological and pathological processes, including lysosomal trafficking, neurodegeneration, and immune responses. Recent studies have highlighted that LAMP5 may influence neuroinflammatory pathways and affect neuronal survival, suggesting its potential involvement in neurological disorders. The research on LAMP5 recombinatorial proteins aims to elucidate their structure-function relationships and interaction networks, which could provide insights into their roles in disease mechanisms. Additionally, characterizing LAMP5’s interactions with other cellular components may offer new therapeutic targets for treating diseases such as Alzheimer's, Parkinson’s, and other neurodegenerative disorders. By generating recombinant LAMP5 proteins, researchers are able to explore its biochemical properties, cellular localizations, and potential signaling pathways, which are essential for understanding its functions in health and disease. Overall, LAMP5 remains a promising subject of investigation within the fields of cell biology and neurobiology due to its multifaceted roles and implications for human health.
