Analytical Data
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Gene name
MPZ
- Application
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Alternative Names
Myelin peripheral protein ;MPPMyelin protein zero
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Species
Human
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Source
Yeast
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P25189
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Expression Region
30-156aa
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Molecular Weight
16.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MPZ (Myelin Protein Zero) is a crucial protein in the peripheral nervous system, primarily associated with the formation and maintenance of myelin sheaths around nerve fibers. The study of MPZ recombinant proteins has gained significant attention due to their role in myelination and potential implications in demyelinating diseases, such as Charcot-Marie-Tooth disease, which is often linked to mutations in the MPZ gene. These recombinant proteins are essential for understanding the molecular mechanisms underlying myelin sheath formation and function. Researchers are particularly interested in characterizing MPZ for its structural properties and functional roles, as well as its interactions with other myelin proteins and the extracellular matrix. Advanced techniques in protein engineering and expression systems, such as E. coli or mammalian cell lines, facilitate the production of recombinant MPZ, allowing for detailed studies on its biophysical properties and biological activities. By elucidating the structure-function relationship of MPZ, scientists aim to uncover therapeutic targets for demyelinating disorders, paving the way for novel treatment strategies. Furthermore, the development of MPZ-based biosensors or regenerative strategies for nerve repair represents an exciting frontier in neuroscience and regenerative medicine.
