Cat: IPD-X28124

Recombinant Rhesus Macaque REG1B Protein (HEK293),hFc

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Analytical Data

  • 基因名

    REG1B

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Lithostathine-1-beta; PSP-2; REG-1-beta; PSPS2; REGL

  • 种属

    Rhesus Macaque

  • 表达系统

    HEK293

  • 标签

    C-hFc

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    F6SR93

  • 表达区间

    Q23-N166

  • 蛋白长度

    Full Length of Mature Protein

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

REG1B (Regenerating islet-derived 1 beta) is a member of the Reg family of proteins, which are known to play significant roles in regenerative processes, particularly in the context of pancreatic islet cells. Research has shown that REG1B is involved in the regulation of cell proliferation and differentiation, making it a key candidate for studying diabetic conditions and islet regeneration. Elevated expressions of REG1B have been observed in various tumors, suggesting its potential role in oncogenesis and the tumor microenvironment. Furthermore, REG1B’s involvement in inflammatory responses and its secretion by certain cell types underline its dual role in both regeneration and pathology. Understanding the molecular mechanisms of REG1B can provide insights into therapeutic strategies for diabetes mellitus and cancer. Recent studies have employed advanced techniques such as recombinant protein analysis, monoclonal antibody generation, and bioinformatics to elucidate REG1B’s structure and function, paving the way for targeted drug design and regenerative medicine applications. Overall, REG1B represents a fascinating area of research with promising implications for both diabetes treatment and cancer therapy, highlighting the complex interplay between regeneration and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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