Analytical Data
-
Gene name
TMIGD1
-
简介
TMIGD1 is a potential regulator that affects multiple cellular processes, including adhesion, migration, proliferation, and morphology. Its protective effect against oxidative damage in renal epithelial cells promotes cell survival. TMIGD1 Protein, Human (HEK293, Fc) is the recombinant human-derived TMIGD1 protein, expressed by HEK293 , with C-mFc labeled tag.
- Application
-
Alternative Names
Transmembrane and immunoglobulin domain-containing protein 1; TMIGD
-
Species
Human
-
Source
HEK293
-
Tag
C-mFc
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6UXZ0-1
-
Expression Region
V30-P220
-
Protein Length
Extracellular Domain
-
Molecular Weight
47.5 kDa.
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMIGD1 (Transmembrane Immunoglobulin and mucin domain-containing protein 1) is a member of the immunoglobulin superfamily, playing a crucial role in the immune system and cellular signaling. The study of TMIGD1 is primarily driven by its emerging importance in various pathological conditions, including autoimmune diseases and cancer. Recent research indicates that TMIGD1 may influence T-cell receptor signaling and modulate the activation and proliferation of immune cells, highlighting its potential as a therapeutic target. Furthermore, the understanding of its structure-function relationships is essential for unraveling the precise mechanisms by which TMIGD1 exerts its effects on immune responses. The recombinant expression of TMIGD1 not only facilitates the characterization of its biochemical properties but also aids in the development of potential inhibitors or modulators for clinical applications. As such, research focused on the recombination and characterization of TMIGD1 is integral to advancing our knowledge of immune regulation and developing novel therapeutic strategies in immunology.
