Analytical Data
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Gene name
Pepsinogen A4/PGA4
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简介
Pepsinogen A4/PGA4 protein, known for broad substrate specificity, prefers cleaving phenylalanine and leucine bonds but also shows the ability to cleave various other bonds to varying extents. Pepsinogen A4/PGA4 Protein, Human (HEK293, Fc) is the recombinant human-derived Pepsinogen A4/PGA4 protein, expressed by HEK293 , with C-hFc labeled tag.
- Application
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Alternative Names
Pepsin A-4; Pepsinogen-4; PGA4
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Species
Human
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Source
HEK293
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Tag
C-hFc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P0DJD7
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Expression Region
I16-A388
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Protein Length
Full Length of Mature Protein
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Molecular Weight
65-70 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Pepsinogen A4 (PGA4) is a crucial digestive enzyme precursor produced in the gastric mucosa, playing a vital role in protein digestion. As an important member of the pepsinogen family, its activation into pepsin occurs in the acidic environment of the stomach, where it helps break down proteins into peptides, thereby facilitating nutrient absorption. Research on recombinant PGA4 has gained attention due to its potential applications in biotechnology, food industry, and medicine. Understanding the structure and function of PGA4 can lead to advancements in enzyme engineering, enhancing its efficacy and specificity for various industrial processes. Moreover, the study of PGA4 may provide insights into digestive disorders and the development of novel therapeutic strategies. Recombinant protein expression techniques allow for the production of PGA4 in controlled environments, ensuring higher yield and activity, which is crucial for both research and industrial applications. Overall, the exploration of PGA4 presents significant opportunities for scientific innovation and practical applications, highlighting its importance in biochemistry and health sciences.
