Analytical Data
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基因名
PEX11A
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简介
The PEX11A protein may regulate peroxisome dynamics, affecting peroxisome proliferation and division by promoting the association of coating proteins with the peroxisomal membrane. PEX11A is associated with structural organization and promotes membrane protrusion and elongation at the peroxisomal surface. PEX11A Protein, Human (HEK293, Fc) is the recombinant human-derived PEX11A protein, expressed by HEK293 , with N-mFc labeled tag.
- Application
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别名
Peroxisomal membrane protein 11A; PMP28; Peroxin-11A; PEX11
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种属
Human
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表达系统
HEK293
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标签
N-mFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75192
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表达区间
R106-P219
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蛋白长度
Partial
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分子量
40 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PEX11A is a member of the PEX11 protein family, which plays a crucial role in peroxisome biology, including peroxisome biogenesis and division. Peroxisomes are essential organelles involved in various metabolic processes, such as fatty acid oxidation and reactive oxygen species detoxification. Dysregulation of peroxisome functions is linked to several metabolic disorders and neurodegenerative diseases. Research has shown that PEX11A is involved in the proliferation of peroxisomes in response to various metabolic cues, highlighting its significance in maintaining cellular homeostasis. Understanding the mechanisms by which PEX11A functions can provide insights into peroxisome dynamics and the potential therapeutic targets for diseases associated with peroxisome dysfunction. Furthermore, as an important model for studying organelle dynamics, recombinant PEX11A proteins are being utilized in various experimental systems to elucidate their structural and functional properties. This research aims to unravel the molecular interactions and pathways regulated by PEX11A, thereby enhancing our understanding of peroxisome-related pathologies and contributing to the development of innovative therapeutic strategies.
