Analytical Data
-
基因名
Pepsinogen C/PGC
-
简介
Pepsinogen C/PGC protein hydrolyzes various proteins, playing a crucial role in digestion by breaking them down into smaller peptides. Its proficiency in protein hydrolysis contributes to the initial stages of digestion, making it vital in the overall digestive cascade. Pepsinogen C/PGC Protein, Human (His) is the recombinant human-derived Pepsinogen C/PGC protein, expressed by E. coli , with N-His labeled tag.
- Application
-
别名
Gastricsin; Pepsinogen C; PGC; PEPC
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P20142-1
-
表达区间
I153-I239
-
蛋白长度
Partial
-
分子量
10 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Pepsinogen C (PGC) is an important precursor of pepsin, an enzyme that plays a crucial role in protein digestion in the stomach. The study of PGC has garnered significant interest due to its potential implications in both digestive health and various pathological conditions, including gastrointestinal disorders and certain cancers. PGC exists in several isoforms, influenced by genetic variations and environmental factors. Recombinant PGC production allows researchers to investigate its structure-function relationships, enzymatic activity, and regulatory mechanisms in greater detail. Advances in molecular biology techniques have enabled the successful expression of recombinant PGC in various host systems, facilitating the assessment of its functional properties and interactions with other biochemical pathways. Furthermore, understanding the role of PGC in the digestive system can aid in identifying novel therapeutic targets for metabolic diseases. As a result, research on recombinant PGC is not only essential for fundamental biochemical knowledge but also for its potential applications in clinical settings, including diagnostic markers and targeted treatments for digestive disorders.
