Analytical Data
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Gene name
MMGT1
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简介
The MMGT1 protein is an important member of the endoplasmic reticulum membrane protein complex (EMC) and is essential for the independent insertion of newly synthesized membrane proteins into the endoplasmic reticulum (ER) membrane. Its preference for transmembrane domains with weak hydrophobicity or unstable characteristics guides co- and post-translational insertion processes. MMGT1 Protein, Human (HEK293, His) is the recombinant human-derived MMGT1 protein, expressed by HEK293 , with N-His labeled tag.
- Application
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Alternative Names
ER membrane protein complex subunit 5; Transmembrane protein 32; EMC5; TMEM32
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Species
Human
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Source
HEK293
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N4V1-1
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Expression Region
E66-R131
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Protein Length
Partial
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Molecular Weight
23-29 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MMGT1, a member of the Major Facilitator Superfamily (MFS), plays a significant role in the transport of various substrates across cellular membranes. Research into MMGT1 has emerged due to its crucial involvement in important physiological processes and its potential implications in various health conditions, including metabolic disorders and cancer. The protein operates primarily as a transporter for metabolites and ions, contributing to cellular homeostasis and signaling pathways. Investigating the structure and function of MMGT1 has been of great interest to scientists, as understanding its mechanism can reveal insights into its regulatory roles and potential therapeutic targets. Recent advancements in recombinant protein technology have enabled the production and purification of MMGT1, facilitating in-depth studies of its biochemical properties and transport mechanisms. These studies are essential not only for elucidating the specific substrates transported by MMGT1 but also for exploring its interactions with other cellular proteins. Additionally, the knowledge gained from MMGT1 research can enhance our understanding of similar transporters in other organisms, paving the way for the development of novel strategies to modulate transporter function for therapeutic purposes. Overall, the investigation of MMGT1 recombinant protein serves as a valuable avenue for advancing our understanding of membrane transport processes in health and disease.
