Analytical Data
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基因名
MDGA2
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简介
The MDGA2 protein is involved in cell-cell interactions, suggesting a role in important connections between cells. Its interaction with NLGN2 is facilitated by its Ig-like domain, specifically involving the formation of molecular associations with NLGN2 that may affect cell communication or adhesion. MDGA2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MDGA2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
MAM domain containing glycosylphosphatidylinositol anchor 2; MAMDC1; MDGA2
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P60755
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表达区间
P26-D924
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蛋白长度
Full Length of Mature Protein
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分子量
110-120 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MDGA2 (Mammalian Derailed-1 Family Protein 2) is a member of the immunoglobulin superfamily that plays a crucial role in various biological processes, including neuronal development and axon guidance. The study of MDGA2 is particularly significant due to its involvement in the regulation of cell adhesion and migration, which are essential for proper nervous system function. Aberrant expression of MDGA2 has been linked to neurodevelopmental disorders and certain cancers, highlighting its potential as a biomarker and therapeutic target. Recombinant MDGA2 proteins are synthesized for in-depth studies to elucidate their structure-function relationships, interaction with other proteins, and signaling pathways. Furthermore, these studies can provide insights into the molecular mechanisms underlying MDGA2's role in cellular processes, aided by techniques such as X-ray crystallography, NMR spectroscopy, and functional assays. Understanding MDGA2's biological functions and mechanisms may yield new avenues for therapeutic interventions in diseases where MDGA2 is implicated, thus warranting ongoing research into its recombinant forms and potential biotechnological applications.
