Analytical Data
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基因名
LRRTM3
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简介
The LRRTM3 protein may contribute to the development and maintenance of the vertebrate nervous system, and in vitro studies highlight its synaptic activity. LRRTM3 specifically affects the differentiation of excitatory presynaptic elements, emphasizing its role in shaping synaptic connections associated with excitatory neurotransmission. LRRTM3 Protein, Mouse (CHO, His) is the recombinant mouse-derived LRRTM3 protein, expressed by CHO , with C-His labeled tag.
- Application
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别名
Leucine-rich repeat transmembrane neuronal protein 3; LRRTM3
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种属
Mouse
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表达系统
CHO
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8BZ81-1
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表达区间
E31-H419
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蛋白长度
Extracellular Domain
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分子量
46 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LRRTM3 (Leucine-rich repeat transmembrane protein 3) is a member of the leucine-rich repeat protein family, which plays a crucial role in synapse formation and neuronal connectivity. This protein has garnered attention due to its involvement in various neural processes and its potential implications in neurodevelopmental disorders. Research has shown that LRRTM3 can interact with presynaptic and postsynaptic proteins, highlighting its significance in mediating synaptic transmission and plasticity. Additionally, genetic studies have linked LRRTM3 to conditions such as schizophrenia and autism, suggesting that disruptions in its function may contribute to the pathophysiology of these disorders. Consequently, the recombinant expression and characterization of LRRTM3 have become essential for elucidating its structural and functional properties. Understanding the molecular mechanisms underlying LRRTM3's role in synaptic biology could pave the way for developing therapeutic strategies aimed at ameliorating synaptic dysfunction in various neuropsychiatric conditions. Researchers are focused on producing recombinant LRRTM3 in suitable expression systems to facilitate a deeper understanding of its interactions and functional implications at the synapse, ultimately providing insights that could inform the treatment of related disorders.
