Analytical Data
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Gene name
SDPR
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简介
SDPR proteins complexly regulate caveolae biogenesis and morphology, inducing membrane curvature of specialized caveolae.Tissue-wise, it is critical for caveolae in lung and fat endothelial cells, but not in cardiac endothelial cells.SDPR Protein, Mouse (His) is the recombinant mouse-derived SDPR protein, expressed by E.coli , with N-His labeled tag.
- Application
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Alternative Names
Caveolae-associated protein 2; Cavin-2; Phosphatidylserine-binding protein; SDR
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q63918
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Expression Region
G2-A180
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Protein Length
Partial
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Molecular Weight
28 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of SDPR (Serum Deprivation Response Protein) as a recombinant protein has gained significant attention due to its potential roles in cellular processes such as apoptosis, cell proliferation, and stress response. Initially identified as a response to serum deprivation in various cell types, SDPR is believed to be involved in regulating cellular lipid metabolism and membrane dynamics, which are crucial for maintaining cellular homeostasis. Abnormal SDPR expression has been linked to various diseases, including cancer and cardiovascular disorders, suggesting its importance in disease pathophysiology. Recent advancements in recombinant protein technology have enabled the production of SDPR in controlled environments, allowing researchers to investigate its structural attributes and functional mechanisms in detail. This research aims to elucidate how SDPR interacts with other cellular components and its potential as a biomarker or therapeutic target. Understanding the role of SDPR in the cellular context could lead to novel insights into its contribution to health and disease, paving the way for innovative therapeutic interventions that leverage its biological functions. As studies continue to expand, comprehending the intricacies of SDPR's function in various biological processes will be imperative for harnessing its potential in clinical applications.
