Analytical Data
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基因名
TRIP10/CIP4
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简介
TRIP10/CIP4 proteins coordinate cellular dynamics and are critical for insulin-induced GLUT4 translocation and membrane tubulation during endocytosis. Good at lipid binding, especially with phosphatidylinositol 4,5-bisphosphate and phosphatidylserine, promoting membrane invagination. TRIP10/CIP4 Protein, Human (sf9, His) is the recombinant human-derived TRIP10/CIP4 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- Application
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别名
Cdc42-interacting protein 4; Protein Felic; hSTP; TRIP-10; CIP4; STOT; STP
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种属
Human
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表达系统
Baculovirus
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15642
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表达区间
M1-N545
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蛋白长度
Partial
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分子量
84.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRIP10/CIP4 (T-cell receptor interacting protein 10/CIP4 homolog) is a member of the BAR domain-containing protein family, which plays a crucial role in various cellular processes, including membrane trafficking, cytoskeletal organization, and cell signaling. Recent studies have indicated that TRIP10/CIP4 is involved in the regulation of cell proliferation, differentiation, and apoptosis, making it a significant focus of research in cancer biology and immunology. Its ability to interact with several signaling molecules and adaptors suggests its potential role in modulating intracellular pathways that affect cell function and survival. Moreover, alterations in TRIP10/CIP4 expression levels have been linked to various diseases, including tumorigenesis and autoimmune disorders. Understanding the molecular mechanisms underlying TRIP10/CIP4 activities may provide insights into disease etiology and novel therapeutic targets. The investigation of this recombinant protein encompasses both its structural and functional properties, enabling researchers to elucidate its biological roles and potential applications in targeted therapies. By employing techniques such as protein purification, crystallography, and functional assays, scientists aim to dissect the intricate pathways influenced by TRIP10/CIP4 and its implications in health and disease.
