Analytical Data
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基因名
TGFBR2/TGF-beta RII
- Application
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别名
TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II
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种属
Human
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P37173
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表达区间
T23-D159
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蛋白长度
Partial
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分子量
25-45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TGFBR2, or Transforming Growth Factor Beta Receptor II, is a critical component of the TGF-β signaling pathway, which plays a pivotal role in regulating various cellular processes, including cell proliferation, differentiation, and immune response. Dysregulation of TGFBR2 is associated with several pathological conditions, such as cancer, fibrosis, and autoimmune diseases. The study of recombinant TGFBR2 proteins has gained significant interest in recent years due to their potential applications in therapeutic interventions and as biomarkers for disease progression. Recombinant TGFBR2 can be used to investigate the molecular mechanisms underlying TGF-β signaling, enabling researchers to discern how mutations or altered expression levels contribute to disease states. Additionally, these proteins serve as valuable tools in drug discovery, allowing for the screening of potential inhibitors or modulators of TGF-β signaling pathways. Understanding the structure and function of recombinant TGFBR2 can provide insights into its role in various physiological and pathological processes, paving the way for novel therapeutic strategies targeting TGF-β signaling in diseases where it is implicated.
