Analytical Data
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Gene name
p63/TP73L
- Application
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Alternative Names
Chronic ulcerative stomatitis protein ;CUSPKeratinocyte transcription factor KETTransformation-related protein 63 ;TP63Tumor protein p73-like ;p73Lp40p51
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H3D4
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Expression Region
1-680aa
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Molecular Weight
80.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
p63 and TP73L are members of the p53 protein family, which play significant roles in cellular processes such as development, differentiation, and responses to stress. p63 is known for its critical role in the development of ectodermal tissues and is involved in the regulation of epidermal stem cells. TP73L, a variant of the TP73 gene, shares structural and functional similarities with p53 but is primarily involved in neurogenesis and apoptosis. The study of recombinant proteins like p63 and TP73L is crucial for understanding their specific functions and interactions within cellular pathways. Research has revealed that dysregulation of p63 and TP73L can contribute to various diseases, including cancer. Therefore, generating recombinant versions of these proteins allows for in-depth biochemical analysis, structural studies, and exploration of their potential as therapeutic targets. This knowledge is essential for developing novel strategies in regenerative medicine and cancer therapy. The investigation of p63 and TP73L also provides insights into the evolutionary aspects of the p53 family, contributing to a broader understanding of cellular responses across different species. Overall, the research on p63 and TP73L recombinant proteins is pivotal in elucidating their roles in health and disease.
