Cat: IPD-X27912

Recombinant Human GNAZ Protein,His

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Analytical Data

  • 基因名

    GNAZ

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    GN-AZ; Guanine Nucleotide Binding Protein Alpha Z; G(x) alpha chain

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 95% as determined by SDS-PAGE.

  • 蛋白编号

    P19086

  • 表达区间

    Gly2~Val219

  • 分子量

    28kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GNAZ, or Guanine nucleotide-binding protein, alpha Z, is a member of the G protein family that plays a pivotal role in signal transduction pathways, particularly in mediating the actions of various receptors, including G protein-coupled receptors (GPCRs). Research on GNAZ has increasingly gained attention due to its involvement in critical physiological processes such as neurotransmission, hormone signaling, and sensory perception. Unlike other G protein subtypes, GNAZ primarily functions in specific tissues, particularly in the brain and immune system, influencing cellular responses through various downstream effectors. The study of GNAZ-recombinant proteins has significant implications for understanding the molecular mechanisms underpinning these signaling pathways. Furthermore, GNAZ has been implicated in certain pathological conditions, including neurological disorders and cancer, making it a target for therapeutic interventions. The development of GNAZ-recombinant proteins allows researchers to dissect its functional properties, investigate its interactions with different ligands and receptors, and explore its potential as a biomarker or therapeutic target. By utilizing advanced techniques such as gene cloning, affinity purification, and functional assays, researchers aim to elucidate the intricate role of GNAZ in cellular signaling and its broader implications for health and disease, contributing to the growing body of knowledge in molecular biology and pharmacology.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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