Analytical Data
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基因名
SPRR2B
- Application
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别名
Sprr2bSmall proline-rich protein 2B
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O70554
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表达区间
1-98aa
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分子量
17.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPRR2B (Small Proline-Rich Protein 2B) is a member of the small proline-rich protein family, which plays a crucial role in the structural integrity of epithelial tissues. Its expression is often associated with various physiological processes, including cellular differentiation, growth, and stress response. Research has shown that SPRR2B is particularly abundant in keratinocytes, where it is involved in the formation of the cornified envelope, a key component of the skin barrier. Dysregulation of SPRR2B has been linked to skin disorders, such as psoriasis and atopic dermatitis, making it a potential biomarker for these conditions. Additionally, the protein has garnered attention in cancer research, as altered expression of SPRR2B has been observed in various tumors. The study of recombinant SPRR2B protein allows for detailed investigations into its biophysical properties, interaction with cellular components, and functional roles in disease mechanisms. By producing and characterizing SPRR2B in a controlled environment, researchers aim to elucidate its contributions to keratinocyte biology and its potential as a therapeutic target or diagnostic tool for skin-related diseases and cancers. These investigations not only enhance our understanding of epithelial biology but also provide insights into developing novel strategies for disease prevention and treatment.
