Analytical Data
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基因名
PNLIPRP1
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简介
The PNLIPRP1 protein acts as an inhibitor of dietary triglyceride digestion and lacks lipase activity on various substrates. This regulatory effect suggests an effect on the breakdown of dietary triglycerides. PNLIPRP1 Protein, Dog (P.pastoris, His) is the recombinant dog-derived PNLIPRP1 protein, expressed by P. pastoris , with N-His labeled tag.
- Application
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别名
PNLIPRP1; PLRP1; Inactive pancreatic lipase-related protein 1; PL-RP1
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种属
Dog
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表达系统
P. pastoris
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P06857
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表达区间
K18-C467
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氨基酸序列
KEVCYEQIGCFSDAEPWAGTAIRPLKVLPWSPERIGTRFLLYTNKNPNNFQTLLPSDPSTIEASNFQTDKKTRFIIHGFIDKGEENWLLDMCKNMFKVEEVNCICVDWKKGSQTSYTQAANNVRVVGAQVAQMLSMLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEASFQGTPEEVRLDPTDADFVDVIHTDAAPLIPFLGFGTSQQMGHLDFFPNGGEEMPGCKKNALSQIVDLDGIWEGTRDFVACNHLRSYKYYSESILNPDGFASYPCASYRAFESNKCFPCPDQGCPQMGHYADKFAVKTSDETQKYFLNTGDSSNFARWRYGVSITLSGKRATGQAKVALFGSKGNTHQFNIFKGILKPGSTHSNEFDAKLDVGTIEKVKFLWNNNVVNPTFPKVGAAKITVQKGEEKTVHSFCSESTVREDVLLTLTPC
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蛋白长度
Full Length of Mature Protein
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PNLIPRP1, or pancreatic lipase-related protein 1, is primarily expressed in the pancreas and plays a crucial role in lipid metabolism and digestion. As a member of the lipase gene family, PNLIPRP1 is particularly interesting due to its unique enzymatic properties and its potential implications in various metabolic disorders, including obesity and type 2 diabetes. Research has shown that PNLIPRP1 is involved in the hydrolysis of triglycerides, contributing to the regulation of energy homeostasis. Given the rising global burden of metabolic diseases, studying PNLIPRP1 could provide insights into the mechanisms underlying lipid dysregulation. By understanding its structure-function relationships and regulatory mechanisms, researchers aim to explore therapeutic avenues for interventions targeting lipid metabolism. Additionally, recombinant protein technology allows for the production of PNLIPRP1 in sufficient quantities for detailed biochemical and functional studies. This includes assessing its enzyme kinetics, substrate specificity, and potential inhibitory pathways. Overall, PNLIPRP1 represents a promising target for further research in metabolic disease treatment, necessitating a comprehensive understanding of its biological functions and interactions within the metabolic network.
