Analytical Data
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基因名
LMW-PTP/ACP1
- Application
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别名
HAAP; Low Molecular Weight Phosphotyrosine Protein Phosphatase; Adipocyte acid phosphatase; Red cell acid phosphatase 1; LMW-PTPase
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9D358
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表达区间
Met1~Tyr158
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分子量
22kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LMW-PTP (Low Molecular Weight Protein Tyrosine Phosphatase) and ACP1 (Acidic Calmodulin-Binding Protein-1) are pivotal enzymes in cell signaling pathways, playing crucial roles in regulating cellular responses through the dephosphorylation of tyrosine residues on proteins. The study of these proteins is particularly important due to their involvement in various physiological processes, including cell growth, differentiation, and metabolism, as well as their potential link to diseases such as cancer and diabetes. LMW-PTP, being a member of the protein tyrosine phosphatase family, has been implicated in oxidative stress responses and has shown interactions with oncogenes and tumor suppressors, suggesting its relevance in cancer biology. On the other hand, ACP1 is known for its role in signal transduction and calcium signaling pathways, influencing processes such as neuronal function and immune response. The generation of recombinant proteins for LMW-PTP and ACP1 allows for detailed biochemical and structural studies, enabling researchers to unravel their mechanisms of action, investigate their functions in various cellular contexts, and explore their potential as therapeutic targets. By utilizing recombinant DNA technology, these proteins can be produced in a controlled manner, providing a platform for high-throughput screening and compound identification that could lead to novel treatment strategies. Understanding the intricacies of LMW-PTP and ACP1 through recombinant protein studies not only deepens our comprehension of cell signaling mechanisms but also opens avenues for developing new interventions in diseases where these pathways are dysregulated.












