Cat: IPD-X31002

Recombinant Human Kallikrein-7 Protein (Yeast),His

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Analytical Data

  • 基因名

    Kallikrein-7

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Serine protease 6Stratum corneum chymotryptic enzyme ;hSCCE

  • 种属

    Human

  • 表达系统

    Yeast

  • 标签

    N- His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P49862

  • 表达区间

    28-253aa

  • 分子量

    26.7 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Kallikrein-7 (KLK7) is a member of the kallikrein family of serine proteases, which play a crucial role in various physiological processes, including skin homeostasis, inflammation, and tissue remodeling. KLK7 is predominantly expressed in the skin and is implicated in the degradation of keratin, a key structural protein in the epidermis. Research has demonstrated that altered expression of KLK7 is associated with several dermatological conditions, including psoriasis, dermatitis, and skin cancer. The interest in KLK7 as a therapeutic target has grown, particularly due to its potential role in mediating inflammatory responses and promoting keratinocyte proliferation. Furthermore, KLK7 has been suggested as a biomarker for certain diseases, making it a focal point in diagnostic research. To investigate its functions and develop potential therapeutic applications, researchers have focused on producing recombinant KLK7 protein. This involves using modern biotechnological methods to express and purify KLK7 in vitro, allowing for in-depth studies of its enzymatic activity, regulation, and involvement in pathophysiological processes. Understanding KLK7's mechanisms could lead to innovative treatments for skin disorders and provide insights into other diseases linked to its dysregulation, highlighting its importance in both basic research and clinical applications.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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