Analytical Data
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基因名
FAM172A
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简介
The FAM172A protein has multiple uses in the regulation of alternative splicing, interacting with AGO2 and CHD7 to coordinate RNA processing and chromatin modification. In addition to its role in splicing, FAM172A stabilizes protein-protein interactions at the chromatin-spliceosome interface, revealing multifaceted functions. FAM172A Protein, Human (HEK293, His) is the recombinant human-derived FAM172A protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
Protein FAM172A; C5orf21
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WUF8-1
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表达区间
Q19-L416
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氨基酸序列
QIQQGGPDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCNLKKVSIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVAEGYGVIVLNPNENYIEVEKPKIHVQSSSDSSDEPAEKRERKDKVSKETKKRRDFYEKYRNPQREKEMMQLYIRENGSPEEHAIYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKNKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFTEASEAKTSSLKPAVTRRSHRIKHEEL
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蛋白长度
Full Length of Isoform-1 Mature Protein
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分子量
40-60 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAM172A, a member of the FAM172 gene family, has garnered attention in recent years due to its potential roles in various biological processes, including cellular proliferation, differentiation, and apoptosis. Its expression levels have been linked to several diseases, particularly in cancer, where aberrant levels may influence tumor growth and progression. The study of FAM172A is critical for understanding its functional significance within cellular pathways and its interaction with other proteins. Researchers have focused on the recombinant production of FAM172A protein to facilitate in-depth functional assays and structural studies. By generating a purified form of this protein, scientists can explore its molecular mechanisms and identify potential binding partners. Additionally, recombinant FAM172A can be utilized in developing therapeutic strategies aimed at modulating its activity in disease contexts. As research progresses, understanding the role of FAM172A can pave the way for novel insights into pathophysiological conditions and highlight its potential as a biomarker or therapeutic target.
