Recombinant Mouse Arginase-2/ARG2 Protein，His

Arginase-2 (ARG2) is a crucial enzyme that plays a significant role in the urea cycle, responsible for the conversion of arginine to ornithine and urea. This enzyme has gained attention due to its involvement in various physiological and pathological processes, including immune regulation, cancer progression, and cardiovascular diseases. While Arg 1, the other isoform of arginase, primarily operates in the liver, ARG2 is expressed in several tissues and exhibits unique regulatory mechanisms, particularly in immune cells and the tumor microenvironment. The overexpression of ARG2 has been linked to tumor growth and metastasis, as it can modulate the availability of arginine, an amino acid essential for T-cell function and proliferation. Consequently, ARG2 has emerged as a potential therapeutic target, leading to increasing interest in the development of recombinant ARG2 proteins for studying its molecular function, interactions, and potential as a biomarker or therapeutic agent. Characterizing recombinant ARG2 not only enhances the understanding of its enzymatic activity but also facilitates the exploration of its role in various diseases, paving the way for novel treatment strategies aimed at manipulating nitrogen metabolism in pathological conditions.