Recombinant Human APOBEC3A Protein (Yeast)，His

APOBEC3A (A3A) is a member of the APOBEC3 family of cytidine deaminases, which play critical roles in the innate immune response against retroviruses and other pathogens. A3A is particularly known for its ability to edit viral genomes, thereby inhibiting viral replication. In recent years, research has focused on understanding the structure, function, and mechanisms of A3A in both antiviral defense and its involvement in genomic mutations linked to cancer. Mutations induced by A3A can contribute to the genomic instability seen in various cancers, driving tumorigenesis through the alteration of critical genes. Given these dual roles, A3A presents a compelling target for therapeutic interventions. Researchers have been investigating the expression patterns and regulatory mechanisms governing A3A, as well as its interactions with other cellular proteins and its potential as a biomarker for cancer diagnosis and prognosis. Furthermore, studies have employed recombinant A3A protein to explore its enzymatic activity and substrate specificity, contributing to the development of strategies to harness or inhibit its activity for therapeutic use. Understanding A3A's dual nature is essential for developing approaches to mitigate its oncogenic potential while leveraging its antiviral properties.