Analytical Data
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基因名
MFAP4
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简介
MFAP4 is a protein that may be involved in calcium-dependent cell adhesion or cell-cell interactions and may play a role in elastic fiber assembly and maintenance. It exists as homodimers and is capable of forming higher oligomers. MFAP4 Protein, Human (HEK293, His-Flag) is the recombinant human-derived MFAP4 protein, expressed by HEK293 , with N-His, N-Flag labeled tag.
- Application
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别名
Microfibril-associated glycoprotein 4; Mfap4
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种属
Human
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表达系统
HEK293
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标签
N-8*His;N-Flag
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55083-1
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表达区间
V22-A255
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蛋白长度
Full Length of Isoform-1 Mature Protein
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分子量
35-45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MFAP4 (Microfibril-associated protein 4) is a protein that plays a significant role in the extracellular matrix, particularly in the formation and stabilization of elastic fibers. Its involvement in various biological processes, such as tissue repair and cardiovascular health, has garnered increasing interest in recent years. MFAP4 is believed to interact with other proteins within the extracellular matrix, contributing to cellular adhesion and the structural integrity of tissues. Abnormal expression or mutation of MFAP4 has been linked to several pathological conditions, including cardiovascular diseases and age-related degeneration, highlighting its potential as a biomarker for these disorders. Research on recombinant MFAP4 has focused on understanding its molecular mechanisms, interactions with other matrix proteins, and its role in disease progression. By producing this protein recombinantly, scientists can conduct detailed studies on its structure-function relationship and potential therapeutic applications. Furthermore, recombinant MFAP4 serves as a valuable tool for exploring the dynamics of extracellular matrix organization and its implications in tissue engineering and regenerative medicine. As studies continue to unfold, MFAP4 may emerge as a promising candidate for novel diagnostic and therapeutic interventions in related diseases, paving the way for advancements in the field of molecular medicine.
