Analytical Data
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基因名
SLPI
- Application
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别名
ALK1; ALP; MPI; BLPI; HUSI; HUSI-I; WAP4; WFDC4; Antileukoproteinase; Seminal proteinase inhibitor; Mucus proteinase inhibitor; WAP four-disulfide core domain protein 4
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P97430
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表达区间
Pro20~Met131
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分子量
20kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of SLPI (Secretory Leukocyte Protease Inhibitor) recombinant protein is grounded in its significant role in the innate immune system. SLPI is a 14 kDa protein primarily produced by epithelial cells and is known for its ability to inhibit serine proteases, which are enzymes that can cause tissue damage during inflammatory responses. Its protective functions are critical in conditions such as respiratory infections, where it plays a pivotal role in maintaining mucosal integrity and modulating immune responses. Research has revealed that SLPI not only protects tissues from enzymatic degradation but also possesses antimicrobial properties and can influence the activity of immune cells. Given its multifaceted role in pathophysiological processes, including chronic inflammatory diseases and certain cancers, there is considerable interest in the potential therapeutic applications of SLPI. The recombinant production of SLPI allows for detailed structural and functional studies, enabling researchers to explore its mechanisms of action, develop SLPI-based therapeutics, and expand our understanding of its role in disease modulation. Moreover, the recombinant technology enhances the availability and purity of SLPI, making it a valuable tool for both basic research and clinical applications.
