Analytical Data
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Gene name
TLR2
- Application
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Alternative Names
CD282; TIL4; Toll/interleukin-1 receptor-like protein 4
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Species
Human
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Source
E. coli
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Tag
Two N- s, His- & SUMO-
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60603
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Expression Region
Pro47~Gly245
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Molecular Weight
38.0kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Toll-like receptor 2 (TLR2) is a crucial component of the innate immune system, recognizing various pathogen-associated molecular patterns (PAMPs) from bacteria, viruses, and fungi. Research into TLR2 has gained significant attention due to its role in modulating immune responses and its involvement in various infectious and inflammatory diseases. TLR2 recognizes ligands such as lipoproteins and peptidoglycans, initiating signaling pathways that lead to the production of pro-inflammatory cytokines and the activation of immune cells. The study of recombinant TLR2 proteins has enabled scientists to investigate the receptor's structure-function relationship, ligand-binding interactions, and downstream signaling mechanisms. Recombinant TLR2 proteins serve as valuable tools in understanding the receptor's role in immunological responses, potential therapeutic applications, and vaccine development. Furthermore, characterizing TLR2 through recombinant technology facilitates the exploration of its involvement in autoimmune diseases, chronic inflammation, and cancer, making it a promising target for novel immunotherapeutic strategies. Overall, research on TLR2 recombinant proteins is essential for unveiling new insights into immune regulation and developing strategies for disease intervention.
