Analytical Data
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基因名
IgG2C
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简介
IgG2C Fc is a subclass of IgG2. Mouse IgG2c Fc loop residues have stronger receptor binding affinity than mouse IgG2b or human IgG1. IgG2C Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG2C Fc protein, expressed by HEK293 , with tag free.
- Application
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别名
Ighg2c; IgG2C
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种属
Mouse
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表达系统
HEK293
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
F6TQW2
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表达区间
I97-S330
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蛋白长度
Partial
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分子量
30-40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IgG2C recombinant protein is a variant of immunoglobulin G (IgG) that offers unique properties relevant to research and therapeutic applications. IgG2 is one of the four subclasses of IgG in humans and possesses specific functional characteristics, including differences in effector functions and binding affinity for various antigens. The study of IgG2C, in particular, has garnered attention due to its potential roles in immune response modulation and its implications in vaccine development and antibody-based therapies. The recombinant production of IgG2C allows for detailed analysis of its structure-function relationships and enhances our understanding of antibody mechanisms in different disease contexts. Researchers are particularly interested in the ability of IgG2C to engage with Fc receptors and complement proteins, which are critical for mediating immune responses. Furthermore, advancements in recombinant DNA technology have enabled the efficient production and purification of IgG2C, making it a valuable tool in both basic and applied biomedical research. This protein's unique dynamics and interactions can inform strategies for designing more effective therapeutics, especially against infectious diseases and certain cancers. Additionally, the exploration of IgG2C holds promise for optimizing vaccine formulations to elicit robust and sustained immune responses. As the field of immunology evolves, understanding the intricacies of IgG2C may pave the way for innovative approaches in immunotherapy and enhance our ability to harness the immune system for clinical benefit.












