Analytical Data
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基因名
SLAMF8
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简介
SLAMF8 protein may contribute to B-lineage commitment and modulation of B-cell receptor signaling, playing a crucial role in B-cell development and immune responses. Exploring its molecular mechanisms and downstream effects could provide insights into its significance in B-cell biology. SLAMF8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SLAMF8 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
SLAM family member 8; B-lymphocyte activator macrophage expressed; CD353; Slamf8; Blame
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种属
Mouse
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9D3G2
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表达区间
V21-D231
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氨基酸序列
VQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTGGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRWEGTVDFNGEVRSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKD
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蛋白长度
Extracellular Domain
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分子量
32-38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLAMF8 (Signaling Lymphocytic Activation Molecule Family Member 8) is a member of the SLAM family of proteins, which are involved in immune responses. It primarily functions as an immune regulator, influencing the activation, differentiation, and survival of various immune cells, including T cells and dendritic cells. Recent studies have highlighted the potential role of SLAMF8 in autoimmune diseases and infections; however, its precise mechanisms and interactions within the immune system are not fully understood. Due to its importance in immune regulation, researchers have shown interest in characterizing SLAMF8 through recombinant protein studies. By expressing and purifying SLAMF8 as a recombinant protein, scientists aim to investigate its structural properties, binding interactions, and functional roles in immune signaling pathways. This research could provide valuable insights into how SLAMF8 contributes to immune responses and its potential as a therapeutic target for immune-related disorders. Understanding SLAMF8's function may pave the way for new strategies in treating autoimmune diseases and improving immune system function.
