Recombinant Rat CD93/C1qR1 Protein(HEK293), His

CD93/C1qR1

The CD93/C1qR1 protein is a receptor or component of a larger complex that is critical in immune recognition and response. It acts as a receptor for C1q, mannose-binding lectin (MBL2), and pulmonary surfactant protein A (SPA), suggesting a role in interactions with multiple immune components. CD93/C1qR1 Protein, Rat (HEK293, His) is the recombinant rat-derived CD93/C1qR1 protein, expressed by HEK293 , with C-His labeled tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Measured by its ability to enhance TNF-alpha secretion by THP 1 human acute monocytic leukemia cells. The ED50 for this effect is 6.393 μg/mL, corresponding to a specific activity is 156.421 U/mg. Measured by its ability to enhance TNF-alpha secretion by THP 1 human acute monocytic leukemia cells. The ED50 for this effect is 6.393 μg/mL, corresponding to a specific activity is 156.421 U/mg.

Complement Component C1q Receptor; CD93; C1qRp; Ly-68; C1qr1

Rat

HEK293

C-10*His

Greater than 90% as determined by SDS-PAGE.

Q9ET61

D24-K571

DSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKTKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYKASKSSCISKRCVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQLTYTTPFQATTSSLKAVPFASVANVVCGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCHCPRGYQLDSSQVHCVDIDECEDSPCDQECINTPGGFHCECWVGYQSSGSKEEACEDVDECTAAYSPCAQGCTNTDGSFYCSCKEGYIMSGEDSTQCEDIDECLGNPCDTLCINTDGSFRCGCPAGFELAPNGVSCTRGSMFSELPARPPQKEDKGDGKESTVPLTEMPGSLNGSKDVSNRAQTTDLSIQSDSSTASVPLEIEVSSEASDVWLDLGTYLPTTSGHSQPTHEDSVPAHSDSDTDGQK

Extracellular Domain

75-90 kDa.

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.