Cat: IPD-X20604

Recombinant Cynomolgus CD6 Protein(HEK293), Avi & His

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Analytical Data

  • 基因名

    CD6

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CD6 antigen; Cd6

  • 种属

    Cynomolgus

  • 表达系统

    HEK293

  • 标签

    C-Avi;C-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    XP_005577746

  • 表达区间

    H18-L399

  • 分子量

    63-90 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Langerin, also known as CD207, is a C-type lectin receptor predominantly expressed on Langerhans cells, a specialized subset of dendritic cells found in the epidermis. This receptor plays a critical role in the immune response by mediating the recognition and internalization of pathogens, such as viruses and bacteria, through its carbohydrate-binding activity. Due to its unique properties, Langerin is important for maintaining skin immune surveillance and tolerance. Research on recombinant Langerin/CD207 protein has gained importance for several reasons. First, understanding its structure and function can offer insights into the mechanisms of antigen presentation and T cell activation, crucial for developing novel immunotherapies. Additionally, Langerin's ability to bind to specific glycans makes it a potential target for vaccine development and targeted drug delivery systems. Studies involving recombinant Langerin also pave the way for exploring its role in various skin-related diseases, including infections, allergies, and autoimmune disorders. Furthermore, given the increasing interest in the interplay between the immune system and skin microbiota, Langerin's study may uncover new therapeutic avenues for maintaining skin health and combating dermal-related pathologies. Overall, ongoing research into Langerin/CD207 recombinant protein holds significant promise for advancing our understanding of immunology and therapeutic interventions in dermatological and systemic diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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