Recombinant Human DcR3/TNFRSF6B Protein(Baculovirus) , hFc

DcR3/TNFRSF6B

DcR3 is a secreted member of the Tumor Necrosis Factor (TNF) receptor superfamily, recognized as a significant anti-apoptotic factor with prominent involvement in various inflammatory and neoplastic conditions. DcR3 can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL against apoptosis[1][2][3]. DcR3 has been associated with tumorigenesis and metastasis, via DcR3/STAT1/IRF1 feedback loop[4][5]. DcR3/TNFRSF6B Protein, Human (sf9, hFc) has a full length of 300 amino acids (M1-H300), produced in sf9 insect cells with C-terminal hFc-tag.

SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

Tumor necrosis factor receptor superfamily member 6B; Decoy receptor 3; TNFRSF6B; DCR3; TR6

Human

Baculovirus

C-hFc

Greater than 90% as determined by SDS-PAGE.

O95407

V30-H300

Full Length of Mature Protein

65 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.