Analytical Data
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Gene name
CD164
- Application
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Alternative Names
MGC-24v; Endolyn; CD164 Molecule,Sialomucin; Sialomucin core protein 24; Multi-glycosylated core protein 24
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by reducing SDS-PAGE.
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Uniprot
Q9QX82
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Expression Region
Gln24~Asp160
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Molecular Weight
21kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD164, also known as the sialomucin CD164 or MUC19, is a type I transmembrane protein that is primarily expressed in hematopoietic cells. It plays a crucial role in various biological processes, including cell adhesion, differentiation, and immune response modulation. Researchers have increasingly focused on the study of CD164 due to its potential implications in cancer biology and immunology. Its expression has been associated with various tumors, indicating that it may serve as a biomarker for cancer progression or a therapeutic target. Additionally, CD164 is involved in the regulation of hematopoietic stem cell migration and niche interactions, which are essential for maintaining hematopoiesis. The use of recombinant CD164 protein for experimental purposes enables scientists to investigate its biological functions, receptor interactions, and signaling pathways. By understanding the molecular mechanisms underlying CD164's actions, researchers hope to uncover novel strategies for disease diagnosis and treatment, especially in contexts where immune response or tumorigenesis is affected. Thus, the study of CD164 recombinant protein is crucial for advancing our understanding of immune regulation, tumor biology, and the potential for therapeutic applications in hematological malignancies and solid tumors.
