Analytical Data
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Gene name
ACE/CD143
- Application
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Alternative Names
CD143; ACE1; DCP1; ACEI; ACE-I; Kininase II; Angiotensin-Converting Enzyme; Peptidyl-Dipeptidase A; Dipeptidyl Carboxypeptidase 1; Angiotensin-converting enzyme, soluble form
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Species
Mouse
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Source
E. coli
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Tag
Two N- s, His- & MBP-
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Purity
Greater than 97% as determined by reducing SDS-PAGE.
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Uniprot
P09470
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Expression Region
Tyr504~Asp597
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Molecular Weight
60kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACE (Angiotensin-converting enzyme) and CD143 are synonymous terms that refer to a key enzyme involved in the renin-angiotensin system, which plays a critical role in regulating blood pressure and fluid balance. ACE catalyzes the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, and is implicated in various physiological and pathological processes, including cardiovascular diseases, hypertension, and renal dysfunction. The manipulation of ACE/CD143 through recombinant protein technology has gained significant attention in research, as understanding its structure and function can yield insights into its role in disease mechanisms. Recombinant ACE/CD143 proteins are being developed for various applications, including therapeutic interventions, diagnostic tools, and as research reagents to better understand its biological activities. Additionally, studies focusing on the inhibition or modulation of ACE/CD143 are relevant for developing new treatments for hypertension and other related disorders, making it a vital target for ongoing biomedical research.
