Analytical Data
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基因名
BDKRB2
- Application
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别名
BDKRB2;BKR2;B2 bradykinin receptor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P30411
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表达区间
1-60aa
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氨基酸序列
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQV EWLGWLNTIQ
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BDKRB2, also known as the bradykinin B2 receptor, is a G-protein coupled receptor that plays a significant role in various physiological processes, including inflammation, pain sensation, and vasodilation. Its relevance has been underscored in numerous studies linking it to cardiovascular disease, neuropathic pain, and other pathological conditions. The receptor interacts with the peptide bradykinin, initiating a cascade of cellular responses that modulate local and systemic effects in the body. Research on BDKRB2 recombinant proteins has gained momentum due to their potential therapeutic applications, including in pain management and the treatment of ischemic conditions. By producing and studying BDKRB2 in recombinant systems, researchers aim to elucidate the receptor’s structure-function relationship, explore its signaling pathways, and identify potential drug candidates that can selectively target BDKRB2. Moreover, as BDKRB2 is involved in the body’s response to injury and infection, understanding its mechanisms can provide insights for developing novel anti-inflammatory and analgesic therapies. The advancements in recombinant protein technology facilitate the detailed characterization of BDKRB2, paving the way for innovative approaches in drug discovery and therapeutic interventions targeting this crucial receptor in various diseases.












