Analytical Data
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Gene name
RFPL2
- Application
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Alternative Names
Ret finger protein like 2; Ret finger protein-like 2; RFPL 2; RFPL2; RFPL2_HUMAN; RING finger protein 79; RNF79
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75678
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Expression Region
1-378 aa
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AA Sequence
MEVAELGFPE TAVSQSRICL CAVLCGHWDF ADMMVIRSLS LIRLEGVEGR DPVGGGNLTN KRPSCAPSPQ DLSAQWKQLE DRGASSRRVD MAALFQEASS CPVCSDYLEK PMSLECGCAV CLKCINSLQK EPHGEDLLCC CSSMVSRKNK IRRNRQLERL ASHIKELEPK LKKILQMNPR MRKFQVDMTL DANTANNFLL ISDDLRSVRS GRIRQNRQDL AERFDVSVCI LGSPRFTCGR HCWEVDVGTS TEWDLGVCRE SVHRKGRIQL TTELGFWTVS LRDGGRLSAT TVPLTFLFVD RKLQRVGIFL DMGMQNVSFF DAESGSHVYT FRSVSAEEPL RPFLAPSVPP NGDQGVLSIC PLMNSGTTDA PVRPGEAK
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Molecular Weight
42.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RFPL2, or Repressor of Fragile X Mental Retardation 2, is a member of the RFPL gene family, which is implicated in various cellular processes, including the regulation of gene expression and RNA metabolism. Research into RFPL2 is driven by its potential role in neurodevelopmental disorders, particularly those associated with fragile X syndrome, a leading cause of intellectual disability. The protein is thought to interact with key pathways involved in synaptic function and plasticity, which are critical for cognitive processes. Understanding the structure and function of RFPL2 may provide insights into its regulatory mechanisms and how its dysfunction could contribute to neurodevelopmental disorders. Recent studies have focused on its expression patterns in neural tissues and its potential post-translational modifications, as these factors may influence its activity in neurons. Moreover, the exploration of RFPL2's role in cellular stress responses and its interactions with other proteins could unveil novel therapeutic targets for mitigating the effects of fragile X syndrome and similar conditions. As research progresses, characterizing RFPL2's function at the molecular level may illuminate broader implications for neuronal health and the development of effective interventions for related disorders.
