Analytical Data
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Gene name
GH/Somatotropin
- Application
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Alternative Names
Somatotropin(Growth hormone)(GH)(GH-N)(Growth hormone 1)(Pituitary growth hormone)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P01241
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Expression Region
27-217aa
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Protein Length
Partial
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Molecular Weight
27.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Recombinant human growth hormone (rhGH), also known as somatotropin, has emerged as a significant therapeutic agent in the field of endocrinology and biotechnology. Initially derived from pituitary glands, its clinical use was limited due to the risks of contamination and variability in hormone activity. In the 1980s, advancements in recombinant DNA technology enabled the production of rhGH in bacteria and yeast, providing a safer and more consistent source. The hormone plays a crucial role in growth and metabolism, promoting growth in children with growth hormone deficiencies and aiding in tissue repair and metabolism in adults. Its applications have expanded beyond traditional uses to include treatments for conditions such as Turner syndrome, Prader-Willi syndrome, and cachexia in chronic illnesses. Furthermore, rhGH has gained attention in sports medicine for its potential to enhance athletic performance, leading to discussions about its ethical implications and regulation in sports. Ongoing research aims to better understand its mechanisms, optimize therapies, and explore novel applications, such as in regenerative medicine and age-related disorders. As a result, rhGH represents a pivotal advancement in hormone replacement therapies, improving the quality of life for many patients while continuously evolving with technological advancements in biotechnology.
