Cat: IPD-X13988

Recombinant Human CGB7 Protein(Baculovirus), C-His

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Analytical Data

  • Gene name

    CGB7

  • 简介

    The CGB7 protein is the beta subunit of human chorionic gonadotropin (hCG) and is critical during pregnancy, stimulating steroid synthesis that is essential for maintaining pregnancy. As a unique β subunit, CGB7 confers hCG specificity and plays a unique role in reproductive physiology. CGB7 Protein, Human (sf9, His) is the recombinant human-derived CGB7 protein, expressed by Sf9 insect cells , with C-His labeled tag.

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Choriogonadotropin subunit beta 7; CGB7

  • Species

    Human

  • Source

    Baculovirus

  • Tag

    C-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P0DN87-1

  • Expression Region

    S21-Q165

  • Protein Length

    Full Length of Isoform-1 Mature Protein

  • Molecular Weight

    25 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CGB7 is a member of the chorionic gonadotropin beta-subunit family, which plays a significant role in reproductive biology. This protein is primarily expressed in the placenta and is crucial for maintaining pregnancy by regulating hormone levels essential for fetal development. Recent studies have highlighted the importance of CGB7 in various reproductive disorders, as its expression levels can be altered in conditions such as preeclampsia and gestational trophoblastic diseases. Research into the recombinant production of CGB7 protein has gained traction, aiming to explore its potential therapeutic applications and to better understand its biological functions. By generating recombinant CGB7, scientists can study its structure-function relationships and interactions with other hormonal pathways, paving the way for novel diagnostic and therapeutic interventions related to reproductive health. Moreover, the availability of recombinant CGB7 facilitates the development of specific antibodies for use in clinical settings, enhancing our understanding of its role in pregnancy and related complications. Overall, the study of CGB7 recombinant protein not only sheds light on its biological significance but also opens up new avenues for clinical applications in reproductive medicine.

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