Analytical Data
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基因名
PARVA
- Application
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别名
PARVA;MXRA2;Alpha-parvin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NVD7
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表达区间
1-372aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMATSPQKSPSVPKSPTPKSPPSRKKDD SFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEE NEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQ VLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKW NVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQS RQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLN KLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNV SFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PARVA, also known as Paxillin-Associated Regulator of Vascular Assembly, is a crucial protein implicated in cellular processes such as adhesion, migration, and signal transduction, particularly in vascular development and homeostasis. Research on PARVA has garnered attention for its role in cancer metastasis, where altered expression and function can influence tumor progression and the ability of cancer cells to invade surrounding tissues. Investigations into the structural and functional characteristics of PARVA through recombinant protein studies have provided insights into its interactions with other cellular components, such as focal adhesion proteins and signaling pathways. By utilizing techniques such as molecular cloning and expression in various systems, scientists aim to elucidate the mechanisms by which PARVA regulates cellular behavior and contributes to pathological conditions. The findings have potential implications for developing therapeutic strategies targeting PARVA interactions, thereby enhancing our understanding of not only cancer biology but also broader aspects of cell biology and tissue engineering.
