Analytical Data
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基因名
RD3
- Application
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别名
RD3；C1orf36；Protein RD3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z3Z2
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表达区间
1-195aa
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氨基酸序列
MSLISWLRWNEAPSRLSTRSPAEMVLETLMMELTGQMREAERQQRERSNAVRKVCTGVDYSWLASTPRSTYDLSPIERLQLEDVCVKIHPSYCGPAILRFRQLLAEQEPEVQEVSQLFRSVLQEVLERMKQEEEAHKLTRQWSLRPRGSLATFKTRARISPFASDIRTISEDVERDTPPPLRSWSMPEFRAPKAD
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分子量
30.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of RD3 recombinant protein has garnered significant interest due to its potential role in understanding and addressing various retinal diseases, particularly those linked to inherited retinal dystrophies. RD3, or retinitis pigmentosa 13 protein, is associated with rod and cone photoreceptor function and is crucial for photoreceptor cell integrity. Mutations in the RD3 gene have been implicated in severe forms of blindness, highlighting its importance in retinal health. Recombinant protein studies help elucidate the biochemical pathways involved in RD3 functioning and its interaction with other proteins within the retinal environment. By producing RD3 in a laboratory setting, researchers can investigate its structural properties and cellular mechanisms, paving the way for gene therapy approaches and potential treatments for patients suffering from conditions related to RD3 mutations. Furthermore, understanding the role of RD3 in phototransduction and photoreceptor maintenance could unlock new strategies for combating retinal degenerative diseases, thus contributing to the broader field of regenerative medicine and vision restoration therapies. Overall, RD3 recombinant protein research is crucial for developing targeted interventions, enhancing our understanding of retinal biology, and ultimately improving outcomes for affected individuals.
