Analytical Data
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基因名
LUM
- Application
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别名
LUM;LDC;SLRR2D;Lumican
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51884
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表达区间
1-338aa
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氨基酸序列
MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSA MYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHN LLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKIT KLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP SGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNS FNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN
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分子量
63 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LUM (Lumican) is a small leucine-rich proteoglycan primarily found in the extracellular matrix of connective tissues, playing a crucial role in cellular processes including cell growth, migration, and tissue organization. Its significance in the regulation of collagen fibrillogenesis has made it a focal point in research related to various pathological conditions such as fibrosis, cancer, and cardiovascular diseases. Understanding LUM's structure and function, particularly through the study of recombinant protein, offers valuable insights into its biological mechanics and therapeutic potential. The production of LUM as a recombinant protein allows for the detailed investigation of its interactions with other extracellular matrix components and cell surface receptors, facilitating a deeper understanding of its role in health and disease. Moreover, given the emerging interest in extracellular matrix components as targets in regenerative medicine and tissue engineering, studying LUM provides opportunities to develop novel therapeutic strategies aimed at modulating its activity to improve tissue repair and regeneration. This ongoing research underscores LUM's relevance not only as a biomarker for certain diseases but also as a potential target for innovative treatments, highlighting the importance of thorough scientific exploration in the field of proteoglycans and their complex roles in human physiology.
