Analytical Data
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Gene name
CSF2RB
- Application
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Alternative Names
CSF2RB；IL3RB；IL5RB;Cytokine receptor common subunit beta
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P32927
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Expression Region
17-443aa
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AA Sequence
WERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTGYNGIWSEWSEARSWDTESVLPMW
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Molecular Weight
50.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CSF2RB, also known as the granulocyte-macrophage colony-stimulating factor receptor beta (GM-CSFRβ), is a critical component of the receptor complex that mediates the biological effects of granulocyte-macrophage colony-stimulating factor (GM-CSF). This cytokine plays a vital role in hematopoiesis, immune system regulation, and inflammation. Research into CSF2RB has gained momentum due to its implications in various diseases, including cancers and autoimmune disorders. Mutations or alterations in CSF2RB expression have been associated with hematological malignancies, highlighting its potential as a therapeutic target. Recombinant CSF2RB proteins are essential for elucidating the receptor's structure, function, and signaling pathways. These proteins can be used in functional assays, binding studies, and drug discovery efforts, making them invaluable tools in understanding disease mechanisms and developing novel treatments. As scientists continue to explore the role of CSF2RB in cell signaling and its broader implications in health and disease, the development of high-quality recombinant proteins remains a key focus.
