Analytical Data
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Gene name
RENBP
- Application
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Alternative Names
RENBP；N-acylglucosamine 2-epimerase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P51606
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Expression Region
1-427aa
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AA Sequence
MSKGLPARQD MEKERETLQA WKERVGQELD RVVAFWMEHS HDQEHGGFFT CLGREGRVYD DLKYVWLQGR QVWMYCRLYR TFERFRHAQL LDAAKAGGEF LLRYARVAPP GKKCAFVLTR DGRPVKVQRT IFSECFYTMA MNELWRATGE VRYQTEAVEM MDQIVHWVQE DASGLGRPQL QGAPAAEPMA VPMMLLNLVE QLGEADEELA GKYAELGDWC ARRILQHVQR DGQAVLENVS EGGKELPGCL GRQQNPGHTL EAGWFLLRHC IRKGDPELRA HVIDKFLLLP FHSGWDPDHG GLFYFQDADN FCPTQLEWAM KLWWPHSEAM IAFLMGYSDS GDPVLLRLFY QVAEYTFRQF RDPEYGEWFG YLSREGKVAL SIKGGPFKGC FHVPRCLAMC EEMLGALLSR PAPAPSPAPT PACRGAE
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RENBP (RNA Export and Nuclear Transport factor) is a reconstituted protein that has garnered significant attention in the field of molecular biology due to its crucial role in RNA metabolism, especially in the export of mRNA from the nucleus to the cytoplasm. The study of RENBP is particularly relevant given the importance of RNA processing in the regulation of gene expression and the implications this has in various biological processes, including development and response to environmental stimuli. Research indicates that RENBP interacts with the nuclear pore complex and plays a pivotal role in recognizing and binding to mRNA, facilitating its transport. Disturbances in RNA transport mechanisms have been linked to a range of diseases, including cancer and neurodegenerative disorders, highlighting the therapeutic potential of targeting RENBP pathways. The exploration of RENBP's structure and function not only enhances our understanding of fundamental cellular processes but also provides avenues for innovative strategies in drug development. Recent advancements in recombinant DNA technology and protein expression systems have enabled researchers to produce and analyze RENBP in greater detail, paving the way for future studies aimed at elucidating its precise mechanisms and potential roles in disease. This growing body of research underscores the significance of RENBP as a model for investigating RNA export dynamics and its broader implications in cellular physiology and pathology.
