Analytical Data
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基因名
HIST1H1D
- Application
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别名
(Histone H1c)(Histone H1s-2)
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种属
Human
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表达系统
E. coli
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标签
N- MBP & C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P16402
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表达区间
2-221aa
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分子量
66.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIST1H1D is a member of the histone H1 family, which plays a crucial role in the structure and function of chromatin in eukaryotic cells. Histones are fundamental proteins that help package DNA into a compact, organized structure, enabling efficient gene regulation and cellular processes. The research on HIST1H1D recombinant protein has garnered interest due to its potential implications in understanding epigenetic modifications, chromatin dynamics, and their associated diseases, including cancer. Aberrant expression or mutations in histone proteins can lead to altered gene expression patterns, contributing to tumorigenesis and cellular dysfunction. Furthermore, the characterization of HIST1H1D and its interactions with other chromatin-associated proteins can provide insights into the regulatory mechanisms governing gene expression and cellular differentiation. Researchers utilize recombinant techniques to produce HIST1H1D for various applications, including structural studies, functional assays, and potential therapeutic interventions. Understanding the role of HIST1H1D in chromatin biology is essential for deciphering the complex regulatory networks that drive cellular processes and developing novel strategies for disease treatment and prevention.
