Analytical Data
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Gene name
TAF5L
- Application
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Alternative Names
PCAF-associated factor 65 beta
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75529
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Expression Region
1-325aa
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Molecular Weight
64 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAF5L (TAF5 like) is a member of the TATA-binding protein (TBP)-associated factor (TAF) family, which plays a critical role in the regulation of gene expression and chromatin remodeling. Its significance in transcriptional regulation has garnered attention, as it is involved in the recruitment of RNA polymerase II to promoters, thus influencing various cellular processes, including differentiation, proliferation, and response to environmental signals. Research has shown that TAF5L may participate in specific cellular pathways, potentially linking it to cancer progression and other diseases. The recombinant expression of TAF5L enables detailed biochemical and structural studies to elucidate its function and interactions within the transcriptional machinery. By producing TAF5L as a recombinant protein, scientists aim to investigate its role in transcription regulation, assess its potential interactions with other transcription factors and proteins, and evaluate its impact on cellular processes. Understanding TAF5L's mechanisms could provide insights into its contributions to disease pathology and highlight it as a potential target for therapeutic intervention in conditions where transcriptional regulation is disrupted. Therefore, the research on TAF5L recombinant protein is of great importance for advancing our knowledge of gene regulation and its implications in health and disease.
