Analytical Data
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Gene name
ARL4A
- Application
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Alternative Names
ADP ribosylation factor like 4; ADP ribosylation factor like 4A; ADP ribosylation factor like GTPase 4A; ADP-ribosylation factor-like protein 4A; ARL 4; ARL4; Arl4a; ARL4A_HUMAN
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P40617
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Expression Region
2-200aa
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Molecular Weight
26.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARL4A (ADP-ribosylation factor-like 4A) is a member of the ARF family of GTPases, which play crucial roles in various cellular processes, including vesicle trafficking, cytoskeletal organization, and signal transduction. Originally identified in studies focused on the regulation of membrane dynamics, ARL4A has garnered attention for its potential involvement in cancer biology and other diseases. Research indicates that ARL4A may influence cell proliferation, migration, and invasion by modulating actin cytoskeleton dynamics, particularly through its interaction with other proteins and cellular pathways. Additionally, evidence suggests that ARL4A could affect the activity of downstream effectors related to cell signaling. As the understanding of ARL4A's mechanisms evolves, its potential as a therapeutic target is being explored, particularly in cancer research where aberrant GTPase signaling is frequently implicated. Studies on ARL4A recombinantly expressed proteins aim to elucidate its structure-function relationships and interaction networks, providing insights into the modulation of cellular processes and the potential development of ARL4A-targeted therapies.
