Analytical Data
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Gene name
HOXB4
- Application
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Alternative Names
Homeobox protein Hox-2.6Homeobox protein Hox-2F
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Species
Human
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Source
Yeast
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P17483
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Expression Region
1-251aa
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Molecular Weight
29.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HOXB4 is a member of the Homeobox (HOX) gene family, which plays a crucial role in regulating developmental processes, including cell differentiation and axis formation. Notably, HOXB4 has garnered considerable attention in hematopoietic stem cell (HSC) research due to its ability to enhance the self-renewal and expansion of these cells. Studies have demonstrated that the overexpression of HOXB4 can significantly increase the yield of HSCs during ex vivo cultures, making it a potential candidate for applications in regenerative medicine and gene therapy. Furthermore, HOXB4's interaction with various signaling pathways and transcription factors positions it as a key player in cellular reprogramming and lineage specification. Research involving recombinant HOXB4 protein focuses on elucidating its mechanistic roles and potential therapeutic applications, particularly in addressing blood disorders and improving stem cell transplantation outcomes. By investigating the molecular pathways influenced by HOXB4 and its effects on stem cell biology, scientists hope to harness its properties for developing advanced treatments for leukemia, anemia, and other hematological conditions.
